Corticosteroids are just as effective against acute gout as naproxen, according to a Lancet study.
Dutch researchers randomized 120 patients with monoarticular gout to either naproxen or prednisolone for 5 days. (Gout was confirmed in all patients by the presence of monosodium urate crystals.) After 90 hours' treatment, pain and general disability scores as measured on a visual analogue scale were reduced to a similar extent in both groups.
The authors say their study "provides a strong argument to consider prednisolone as a first treatment option in patients with gout."
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